1471 Diisopropylzinc Diisopropylzinc is an exogenous organozinc compound with the formula C6H14Zn and an average molecular weight of 151.58 g/mol. At room temperature, this substance exists as a solid. Diisopropylzinc belongs to the hydrocarbon derivatives, a superclass within the organic compounds. One recorded protein target for this compound is Superoxide dismutase [Cu-Zn] (SOD1). Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). 625-81-0 5207587 C6H14Zn 268.037170 White powder. 385°C Oral (L49) ; inhalation (L49) ; dermal (L49) Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49) Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49) No indication of carcinogenicity to humans (not listed by IARC). Intermediate Oral: 0.3 mg/kg/day (L134) Chronic Oral: 0.3 mg/kg/day (L134) Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49) Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49) Zinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49) 2009-06-19T21:58:49Z 2026-04-06T12:02:55Z Metallothionein-2 (P02795) Metallothionein-1G (P13640) Metallothionein-1H (P80294) Metallothionein-3 (P25713) Metallothionein-1F (P04733) Metallothionein-1E (P04732) Metallothionein-1X (P80297) Metallothionein-1A (P04731) Metallothionein-1B (P07438) Metallothionein-1M (Q8N339) Metallothionein-4 (P47944) Metallothionein-1L (Q93083) Cysteine-rich protein 1 (P50238) Cysteine-rich protein 2 (P52943) Cysteine-rich protein 3 (Q6Q6R5) Serum albumin (P02768) (L49, A49, L92) Diisopropylzinc Diisopropylzinc true Metallothionein-2 (P02795) Metallothionein-1G (P13640) Metallothionein-1H (P80294) Metallothionein-3 (P25713) Metallothionein-1F (P04733) Metallothionein-1E (P04732) Metallothionein-1X (P80297) Metallothionein-1A (P04731) Metallothionein-1B (P07438) Metallothionein-1M (Q8N339) Metallothionein-4 (P47944) Metallothionein-1L (Q930839) Cysteine-rich protein 1 (P50238) Cysteine-rich protein 2 (P52943) Cysteine-rich protein 3 (Q6Q6R5) Serum albumin (P02768) (L49, A49, L92) CC(C)[Zn]C(C)C C6H14Zn InChI=1S/2C3H7.Zn/c2*1-3-2;/h2*3H,1-2H3; KDUNMLRPPVCIGP-UHFFFAOYSA-N 151.584 150.038697026 Exogenous Solid 11347073 CHEM001252 NS00122787 0 29.629800000000003 14.28583519111458 2 0 0 0 0 3.05 -1.69 3.11e+00 g/l Organic compounds Hydrocarbon derivatives 31 CED0024276 KDUNMLRPPVCIGP-UHFFFAOYSA-N 40000040000000000000000000000000000000000000000000000000000002000000001000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004000000001000000000000000000000000000000000000000000000000000000040000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000400000000000 40000002000400000000000000000008000000800000000080000042000000004000000004400008000008011000000000001000000000042000000000000400000020000000000000000002000400000000000000000400000002000801000000004110800000010000200400000040000000000008008400000100400024400000000000800000000000001010000000000000008000020001002c0000100000800000000000000000000000000040000000000000000000000000000000000400000000000080000000000080000000000000000000000000000000000004000000000001050000008 776t3gAAAAAQAAAAAwAAAAAAAAAHAAAABgAAAIABBgBgAAAAAQMGAGAAAAAD AQYAYAAAAAEDHiAoAAAAAgIGAGAAAAADAQYAYAAAAAEDBgBgAAAAAQMLAAEA AQIAAQMAAwQABAUABAYAQgAAAAAXBAAAAAAAAAAW 2026-09-19T04:00:06Z