1477 Zinc trifluoromethanesulfonate Zinc trifluoromethanesulfonate is a solid exogenous compound with the formula C2F6O6S2Zn and an average molecular weight of 363.55 g/mol. Zinc trifluoromethanesulfonate belongs to the organosulfonic acids and derivatives, a subclass of organic sulfonic acids and derivatives within the organic compounds. It is commonly used as a Lewis acid catalyst. One recorded protein target for this compound is Superoxide dismutase [Cu-Zn] (SOD1); unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). 54010-75-2 104671 C2F6O6S2Zn 361.833190 White powder. Oral (L49) ; inhalation (L49) ; dermal (L49) Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49) Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49) No indication of carcinogenicity to humans (not listed by IARC). Zinc trifluoromethanesulfonate is commonly used as a Lewis acid catalyst. (L539) Intermediate Oral: 0.3 mg/kg/day (L134) Chronic Oral: 0.3 mg/kg/day (L134) Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49) Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49) Zinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49) 2009-06-19T21:58:50Z 2026-04-05T22:30:15Z Metallothionein-2 (P02795) Metallothionein-1G (P13640) Metallothionein-1H (P80294) Metallothionein-3 (P25713) Metallothionein-1F (P04733) Metallothionein-1E (P04732) Metallothionein-1X (P80297) Metallothionein-1A (P04731) Metallothionein-1B (P07438) Metallothionein-1M (Q8N339) Metallothionein-4 (P47944) Metallothionein-1L (Q93083) Cysteine-rich protein 1 (P50238) Cysteine-rich protein 2 (P52943) Cysteine-rich protein 3 (Q6Q6R5) Serum albumin (P02768) (L49, A49, L92) Zinc trifluoromethanesulfonate true Metallothionein-2 (P02795) Metallothionein-1G (P13640) Metallothionein-1H (P80294) Metallothionein-3 (P25713) Metallothionein-1F (P04733) Metallothionein-1E (P04732) Metallothionein-1X (P80297) Metallothionein-1A (P04731) Metallothionein-1B (P07438) Metallothionein-1M (Q8N339) Metallothionein-4 (P47944) Metallothionein-1L (Q930839) Cysteine-rich protein 1 (P50238) Cysteine-rich protein 2 (P52943) Cysteine-rich protein 3 (Q6Q6R5) Serum albumin (P02768) (L49, A49, L92) [Zn++].[O-]S(=O)(=O)C(F)(F)F.[O-]S(=O)(=O)C(F)(F)F C2F6O6S2Zn InChI=1S/2CHF3O3S.Zn/c2*2-1(3,4)8(5,6)7;/h2*(H,5,6,7);/q;;+2/p-2 CITILBVTAYEWKR-UHFFFAOYSA-L 363.547 361.83319492 Exogenous Solid 94493 CHEM001257 NS00088677 57.199999999999996 15.860199999999999 7.451100441863231 2 3 0 -3.4301211369712297 -1 0 3.13 -3.31 1.78e-01 g/l Organic compounds Organic acids and derivatives Organic sulfonic acids and derivatives Organosulfonic acids and derivatives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 776t3gAAAAAQAAAAAwAAAAAAAAARAAAADgAAAIABHiAKAAAAAgEIICIAAAD/ ARAAIAAAAAYIACgAAAADAggAKAAAAAMCBgAgAAAABAkAIAAAAAEJACAAAAAB CQAgAAAAAQggIgAAAP8BEAAgAAAABggAKAAAAAMCCAAoAAAAAwIGACAAAAAE CQAgAAAAAQkAIAAAAAEJACAAAAABCwECAAIDCAICBAgCAgUABQYABQcABQgA CQoACgsIAgoMCAIKDQANDgANDwANEABCAAAAABcEAAAAAAAAABY= 2026-09-19T04:00:06Z