3063 Ridogrel Ridogrel is an exogenous organic compound with the formula C18H17F3N2O3 and an average molecular weight of 366.33 g/mol. It exists as a solid at room temperature. Ridogrel belongs to the trifluoromethylbenzenes, a subclass of benzene and substituted derivatives within the organic compounds. This compound targets thromboxane-A synthase (TBXAS1) and the thromboxane A2 receptor (TBXA2R). Ridogrel inhibits thromboxane A2 synthase and blocks the thromboxane A2/prostaglandin endoperoxide receptors. Thromboxane synthetase produces thromboxane in platelets, which acts as a vasoconstrictor and facilitates platelet clumping. By inhibiting the production and promotion of thromboxane, thrombolysis is reduced. Ridogrel is used for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction, although there are currently no clinical indications for its preferential use over aspirin. 110140-89-1 5362391 C18H17F3N2O3 366.119130 White powder. 8.39e-03 g/L Rapidly absorbed after oral administration (30-60 min) Ridogrel inhibits thromboxane A2 synthase and also blocks the thromboxane A2/prostaglandin endoperoxide receptors. Thromboxane synthetase produces thromboxane in platelets. Thromboxane is a vasoconstrictor and facilitates the clumping of platelets. Therefore by inhibiting the production and promotion of thromboxane, thrombolysis is enhanced. No indication of carcinogenicity to humans (not listed by IARC). Used as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction. 2009-07-21T20:28:39Z 2026-05-14T16:58:45Z 127439 Ridogrel DB01207 true OC(=O)CCCCO\N=C(\C1=CN=CC=C1)C1=CC(=CC=C1)C(F)(F)F C18H17F3N2O3 InChI=1S/C18H17F3N2O3/c19-18(20,21)15-7-3-5-13(11-15)17(14-6-4-9-22-12-14)23-26-10-2-1-8-16(24)25/h3-7,9,11-12H,1-2,8,10H2,(H,24,25)/b23-17+ GLLPUTYLZIKEGF-HAVVHWLPSA-N 366.3344 366.119127035 Exogenous Solid 4.3 HMDB15338 CHEMBL280728 4515025 CHEM002378 DTXSID90872935 NS00068597 5-{[(E)-[(pyridin-3-yl)[3-(trifluoromethyl)phenyl]methylidene]amino]oxy}pentanoic acid 71.78 88.8943 34.94102375669082 9 5 1 3.501608187006648 4.25638291462859 -1 2 3.24 -4.64 8.39e-03 g/l Organic compounds Benzenoids Benzene and substituted derivatives Trifluoromethylbenzenes 121 CED0020300 GLLPUTYLZIKEGF-HAVVHWLPSA-N 40000000000000000800000002000000000000000000000000000000000000000000000000001000000000000002004000000001104000000000000000000000000000000000000000000000000000020000000000100000004000000000000000000014000000000000000100000000000000000000000000000000000000001100000000000800002000000000000000000000000000000000040081000010000000000000000040000084000000040000000040000000000000000200100000008000020001000000400000000000000000000000000600200000000000000000000000000002042000000050400800000002000004000000040000000 503080200112864089000940012820000000140001052000003120628220084c44020010108000000000410802800000046000a4408c32010020643100a04200c6190c000280040000901020107203020005059051011b3240000422400049800e2005270048020040000400c5b40000248080700905e004192808000251000a104400080ef0820808060240882c0008193c081244401482000408000040008100c310000090c00000000860017c65100ac00000894108401080021008c00210810000a404800222018004000401028000000000020050000d000000080003009000481008a180040100001140132000001000308042001e0000000052000000 776t3gAAAAAQAAAAAwAAAAAAAAAaAAAAGwAAAIABCABoAAAAAwEBBgAoAAAA AwQIACgAAAADAgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICCAAo AAAAAwIHACgAAAADAwYAKAAAAAMEBkAoAAAAAwQGQGgAAAADAwEHQCgAAAAD AwZAaAAAAAMDAQZAaAAAAAMDAQZAaAAAAAMDAQZAKAAAAAMEBkBoAAAAAwMB BkAoAAAAAwQGQGgAAAADAwEGQGgAAAADAwEGQGgAAAADAwEGACAAAAAECQAg AAAAAQkAIAAAAAEJACAAAAABCwABIAECKAIBAwADBAAEBQAFBgAGBwAHCCQD CAkqAgMCBwoJCiQDCgtoDAsMaAwMDWgMDQ5oDA4PaAwJECAQEWgMERJoDBIT aAwTFGgMFBVoDBIWABYXABYYABYZAA8KaAwVEGgMQgIAAAAGCwwNDg8KBhES ExQVEBcEAAAAAAAAABY= 2026-09-19T04:00:42Z