3534 Cephalosporin Cephalosporin is an exogenous organic compound with the formula C15H14N4O6S2 and an average molecular weight of 410.43 g/mol. It exists as a solid at room temperature. Cephalosporin belongs to the beta lactams, a subclass of lactams within the organic compounds. This compound is recorded as being released from five sources, including healthcare, pharmaceuticals and veterinary products specifically as beta-lactam antibacterials, household cleaning and consumer products such as other smoking requisites, and electrical and electronic equipment including antennas, video games, and communication cables or conductors. The recorded route of exposure is oral. Cephalosporin interacts with five protein targets. It acts as an inhibitor of Penicillin-binding protein 1A (mrcA), Penicillin-binding protein 1B (mrcB), Peptidoglycan D,D-transpeptidase FtsI (ftsI), and Peptidoglycan D,D-transpeptidase MrdA (mrdA). Additionally, Cephalosporin targets Solute carrier family 15 member 1 (SLC15A1). In the case of Ceftibuten, bactericidal action is exerted by binding to essential target proteins of the bacterial cell wall, which leads to the inhibition of cell-wall synthesis. 97519-39-6 5282242 C15H14N4O6S2 White powder. Rapidly absorbed following oral administration. Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis. A study with radiolabeled ceftibuten administered to 6 healthy adult male volunteers demonstrated that cis-ceftibuten is the predominant component in both plasma and urine. About 10% of ceftibuten is converted to the trans-isomer is approximately 1/8 as antimicrobially potent as the cis-isomer. Route of Elimination: Ceftibuten is excreted in the urine; 95% of the administered radioactivity was recovered either in urine or feces. No indication of carcinogenicity to humans (not listed by IARC). Used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis. It is also indicated for pneumonia, infections of the urinary tract, enteritis and gastroenteritis. [Wikipedia] Overdosage of cephalosporins can cause cerebral irritation leading to convulsions. 2009-07-30T17:58:46Z 2026-05-14T17:00:14Z Ceftibuten C08117 3510 Cephalosporin DB01415 true [H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=C/CC(O)=O)\C1=CSC(N)=N1)C(O)=O C15H14N4O6S2 InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1 UNJFKXSSGBWRBZ-BJCIPQKHSA-N 410.425 410.03547558 Exogenous Solid -1.5 CHEMBL1605 4445418 CHEM002509 DTXSID4045925 NS00079152 (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 162.92 97.02379999999998 38.4976253702732 6 8 4 2.98685022221115 4.686058579408637 -2 3 0.31 -3.77 7.05e-02 g/l Organic compounds Organoheterocyclic compounds Lactams Beta lactams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 776t3gAAAAAQAAAAAwAAAAAAAAAbAAAAHQAAAIABBiA0AAAAAQEEEAAgAAAA AgYAYAAAAAICBgBoAAAAAwMBBgAoAAAAAwQHACgAAAADAwYAKAAAAAMECAAo AAAAAwIGIDQAAAABAQQHAGgAAAADAgEGACgAAAADBAgAKAAAAAMCBgAoAAAA AwQGAGgAAAADAwEGAGAAAAACAgYAKAAAAAMECABoAAAAAwEBCAAoAAAAAwIG QCgAAAADBAZAaAAAAAMDARBAKAAAAAMCBkAoAAAAAwQHAGgAAAADAQIHQCgA AAADAwYAKAAAAAMECABoAAAAAwEBCAAoAAAAAwILAAEAAQIAAgMAAwQoAgQF IAUGIAYHKAIGCAAICQAJCiAKCygCCgwgDA0qAgICCg4NDgQEDg8ADxAgDxEo AgwSJAMSE2gMExRoDBQVaAwVFiAVF2gMBBggGBkgGBooAgUAABcSaAwIAABC AwAAAAYBAgMEBQAEBggABQUTEhcVFBcEAAAAAAAAABY= 2026-09-19T04:00:47Z