3672 Ammonium laureth sulfate Ammonium laureth sulfate is a surfactant often found in shampoos. It can be mildly irritating. (L1888) 32612-48-9 61913 C14H33NO5S 327.48 White powder. Oral (A2880) ; inhalation (A2880) ; dermal (L1889) While ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880) Nitrosamines can enter the body via ingestion, inhalation, or dermal contact. Once in the body, nitrosamines are metabolized by cytochrome P-450 enzymes, which essentially activates them into carcinogens. (A2878, A2879) Not listed by IARC. Certain nitrosamines are classified by IARC as either probably or possibly carcinogenic to humans (Groups 2A and 2B, respectively). (L135) Ammonium laureth sulfate is a surfactant often found in shampoos. (L1888) Ammonium laureth sulfate itself only causes mild irritation. However, it may react to produce nitrosamines, which are believed to be carcinogenic. (L1888, L1890) Ammonium laureth sulfate can cause mild irritation. (L1888) 2009-11-19T01:38:02Z 2026-04-17T16:49:19Z 53474 true Cytochrome P450 2A1 (P11711) Cytochrome P450 2A6 (P11509) Cytochrome P450 2E1 (P05181) NAD(P)H dehydrogenase [quinone] 1 (P15559) (A2878, A2879) N.CCCCCCCCCCCCOCCOS(O)(=O)=O C14H33NO5S InChI=1S/C14H30O5S.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-14-19-20(15,16)17;/h2-14H2,1H3,(H,15,16,17);1H3 OPVLOHUACNWTQT-UHFFFAOYSA-N 327.481 327.207943861 Exogenous Solid 55774 CHEM002592 [2-(dodecyloxy)ethoxy]sulfonic acid amine