3704 Diisoundecyl phthalate Diisoundecyl phthalate (C31H52O4) is an exogenous organic compound with an average molecular weight of 488.74 g/mol. It exists as a liquid at room temperature. Diisoundecyl phthalate belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. Industrially, the compound is used as a plasticizer. It has been recorded in drinking water and water supplies, with oral exposure identified as a recorded route. 85507-79-5 5748789 C31H52O4 488.7 Colorless liquid. Oral (L1903) ; inhalation (L1903) ; dermal (L1903) Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expression. Some phthalates have also been shown to reduce the expression of insulin-like peptide 3 (insl3), an important hormone secreted by the Leydig cell necessary for development of the gubernacular ligament. Animal studies have shown that these effects disrupt reproductive development and can cause a number of malformations in affected young. (A2883) Phthalate esters are first hydrolyzed to their monoester derivative. Once formed, the monoester derivative can be further hydrolyzed in vivo to phthalic acid or conjugated to glucuronide, both of which can then be excreted. The terminal or next-to-last carbon atom in the monoester can also be oxidized to an alcohol, which can be excreted as is or first oxidized to an aldehyde, ketone, or carboxylic acid. The monoester and oxidative metabolites are excreted in the urine and faeces. (A2884) No indication of carcinogenicity to humans (not listed by IARC). Phthalate esters are mainly used as plasticizers, primarily used to soften polyvinyl chloride. They are found in a number of products, including glues, building materials, personal care products, detergents and surfactants, packaging, children's toys, paints, pharmaceuticals, food products, and textiles. Phthalates are used in a variety of household applications such as shower curtains, vinyl upholstery, adhesives, floor tiles, food containers and wrappers, and cleaning materials. Personal care items containing phthalates include perfume, eye shadow, moisturizer, nail polish, liquid soap, and hair spray. (L1903) Phthalate esters are endocrine disruptors. Animal studies have shown that they disrupt reproductive development and can cause a number of malformations in affected young, such as reduced anogenital distance (AGD), cryptorchidism, hypospadias, and reduced fertility. The combination of effects associated with phthalates is called 'phthalate syndrome’. (A2883) Phthalate esters are endocrine disruptors and can cause a number of developmental malformations termed 'phthalate syndrome'. (A2883) 2009-12-04T03:09:55Z 2026-08-22T10:44:16Z true CCCCCCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCC(CCC)C(CC)CCC C31H52O4 InChI=1S/C31H52O4/c1-5-9-10-11-12-13-14-15-16-19-24-34-30(32)28-22-17-18-23-29(28)31(33)35-25-27(21-7-3)26(8-4)20-6-2/h17-18,22-23,26-27H,5-16,19-21,24-25H2,1-4H3 JOHNPRHIYSPRSW-UHFFFAOYSA-N 488.7422 488.386560152 Exogenous Liquid 11.9 16091851 CHEM002620 DTXSID4029565 NS00004781 1-O-dodecyl 2-O-[(2R,3S)-3-ethyl-2-propylhexyl] benzene-1,2-dicarboxylate 52.60000000000001 146.68900000000002 61.20500538530323 23 2 0 -6.655897855747703 0 1 9.45 -7.62 1.16e-05 g/l Organic compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives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 776t3gAAAAAQAAAAAwAAAAAAAAAjAAAAIwAAAIABBgBgAAAAAQMGAGAAAAAC AgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGAGAA AAACAgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICCAAoAAAAAwIG ACgAAAADBAgAKAAAAAMCBkAoAAAAAwQGQGgAAAADAwEGQGgAAAADAwEGQGgA AAADAwEGQGgAAAADAwEGQCgAAAADBAYAKAAAAAMECAAoAAAAAwIIACgAAAAD AgYAYAAAAAICBgBgAAAAAwEGAGAAAAACAgYAYAAAAAICBgBgAAAAAQMGAGAA AAADAQYAYAAAAAICBgBgAAAAAQMGAGAAAAACAgYAYAAAAAICBgBgAAAAAQML AAEAAQIAAgMAAwQABAUABQYABgcABwgACAkACQoACgsACwwADA0gDQ4oAg0P IA8QaAwQEWgMERJoDBITaAwTFGgMFBUgFRYoAhUXIBcYABgZABkaABobABsc ABkdAB0eAB4fAB0gACAhACEiABQPaAxCAQAAAAYPFBMSERAXBAAAAAAAAAAW 2026-09-19T04:00:51Z