3805 Aurovertin D Aurovertin D is an exogenous solid with the formula C25H32O9 and an average molecular weight of 476.52 g/mol. Aurovertin D belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. It acts as a mixed, noncompetitive inhibitor of both ATP synthesis and hydrolysis by targeting the mitochondrial ATP synthase F(1) complex subunit beta (ATP5F1B). By binding to beta-subunits in the F1 catalytic sector, it inhibits the proton-pumping F1F0-ATP synthase, which is responsible for the terminal step of oxidative phosphorylation. Aurovertins are believed to bind with varying affinity to two of the three beta subunits at sites in a cleft between the C-terminal and nucleotide-binding domains. 65256-31-7 6438901 C25H32O9 White powder. Oral, dermal, inhalation, and parenteral (contaminated drugs). (A3101) Aurovertins are a mixed, noncompetitive inhibitors of both ATP hydrolysis and synthesis. They do this by inhibiting the proton-pumping F1F0-ATP synthase by binding to beta-subunits in its F1 catalytic sector. F1F0-ATP synthase is responsible for the terminal step of oxidative phosphorylation. Each ATP synthase complex has three beta subunits, and aurovertins are believed to bind with varying affinity to two subunits on sites in a cleft between the nucleotide-binding and C-terminal domains, thus preventing closure of the catalytic interfaces necessary for the cyclic interconversion of catalytic sites. (A3032, A3033, A3034) No indication of carcinogenicity to humans (not listed by IARC). Aurovertin D is a mycotoxin and antibiotic produced by the fungus Calcarisporium arbuscula. (A3002) 2010-05-12T17:31:41Z 2026-04-06T13:15:08Z true [H]/C(=C(/[H])\C(\[H])=C(/[H])C1=C(C)C(OC)=CC(=O)O1)/C(/[H])=C(/[H])C1OC2(C)C(OC(C)(C2OC(C)=O)C1O)C(C)O C25H32O9 InChI=1S/C25H32O9/c1-14-17(32-20(28)13-19(14)30-6)11-9-7-8-10-12-18-21(29)24(4)23(31-16(3)27)25(5,33-18)22(34-24)15(2)26/h7-13,15,18,21-23,26,29H,1-6H3/b8-7+,11-9+,12-10- UKPVUEBWITXZRF-CDIKDJIESA-N 476.522 476.20463261 Exogenous Solid CHEM002719 NS00125703 120.75000000000001 126.94109999999998 50.4989961884435 8 7 2 12.898585052767586 -3.05785121089147 0 3 3.40 -4.08 3.95e-02 g/l Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates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 776t3gAAAAAQAAAAAwAAAAAAAAAiAAAAJAAAAIABBgA4AAAAAwEEBgA4AAAA AwEEBgA4AAAAAwEEBgA4AAAAAwEEBkAoAAAAAwQGQCgAAAADBAYAYAAAAAED BkAoAAAAAwQIACgAAAADAgYAYAAAAAEDBkBoAAAAAwMBBkAoAAAAAwQIACgA AAADAghAKAAAAAMCBgA4AAAAAwEEBgA4AAAAAwEEBgBgAAAAAwEIACAAAAAC BgAgAAAABAYAYAAAAAEDBgBgAAAAAwEIACAAAAACBgAgAAAABAYAYAAAAAED BgBgAAAAAwEIACgAAAADAgYAKAAAAAMEBgBgAAAAAQMIACgAAAADAgYAYAAA AAMBCABgAAAAAQEGAGAAAAADAQYAYAAAAAEDCABgAAAAAQELAAEqAgMCDgIB AiQDAgMqAgMCAQQDBCQDBAVoDAUGAAUHaAwHCCAICQAHCmgMCgtoDAsMKAIL DWgMAA4kBA4PKgICAgAQDxAEAxARABESABITABIUABQVABUWABYXABYYABgZ ABkaIBobABocKAIWHQAdHgAUHwAfIAAfIQANBGgMHRAAGBIAQgMAAAAGBQcK Cw0EBhESGBYdEAUUEhgWFRcEAAAAAAAAABY= 2026-09-19T04:00:54Z