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<compound>
  <id type="integer">3897</id>
  <title>T3D3842</title>
  <common-name>Fluazinam</common-name>
  <description>Fluazinam is an exogenous organic compound with the formula C13H4Cl2F6N4O4 and an average molecular weight of 465.09 g/mol. It exists as a solid at room temperature. Fluazinam belongs to the trifluoromethylbenzenes, a subclass of benzene and substituted derivatives within the organic compounds. This compound is used as an industrial fungicide (PMC8175224).

The compound has 26 recorded protein targets, including the Aryl hydrocarbon receptor (AHR), C-C motif chemokine 2 (CCL2), C-X-C motif chemokine 10 (CXCL10), and Cytochrome P450 1A1 (CYP1A1). Fluazinam has been released from seven recorded sources: agriculture and land management (pesticides), drinking water and water supply (drinking water), air, dust and atmospheric transport (indoor air), food, food processing and cookware (preparation of malt), building and construction (floors, tents or canopies), and electrical and electronic equipment (electric hearing aids). Recorded exposure routes for the substance include oral, inhalation, and touch.</description>
  <cas>79622-59-6</cas>
  <pubchem-id>91731</pubchem-id>
  <chemical-formula>C13H4Cl2F6N4O4</chemical-formula>
  <weight>465.09</weight>
  <appearance>White powder.</appearance>
  <melting-point></melting-point>
  <boiling-point></boiling-point>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Inhalation and dermal contact.</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity></mechanism-of-toxicity>
  <metabolism></metabolism>
  <toxicity></toxicity>
  <lethaldose></lethaldose>
  <carcinogenicity>Not listed by IARC.</carcinogenicity>
  <use-source>This is a man-made compound that is used as a pesticide.</use-source>
  <min-risk-level></min-risk-level>
  <health-effects>Fluazinam increases the risks of thyroid gland follicular cell and hepatocellular tumors in rats and mice. According to The Cancer Assessment Review Committee (CARC), there is suggestive evidence of carcinogenicity, but not sufficient to assess human carcinogenic potential.</health-effects>
  <symptoms>Fluazinam can cause eye irritation and moderate skin sensitization. </symptoms>
  <treatment></treatment>
  <created-at type="dateTime">2013-04-25T07:56:51Z</created-at>
  <updated-at type="dateTime">2026-08-19T03:09:31Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia></wikipedia>
  <uniprot-id></uniprot-id>
  <kegg-compound-id>C18578</kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id></ctd-id>
  <stitch-id></stitch-id>
  <drugbank-id></drugbank-id>
  <pdb-id></pdb-id>
  <actor-id></actor-id>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>[O-][N+](=O)C1=CC(=C(Cl)C(=C1NC1=C(Cl)C=C(C=N1)C(F)(F)F)[N+]([O-])=O)C(F)(F)F</moldb-smiles>
  <moldb-formula>C13H4Cl2F6N4O4</moldb-formula>
  <moldb-inchi>InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)</moldb-inchi>
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  <moldb-average-mass type="decimal">465.092</moldb-average-mass>
  <moldb-mono-mass type="decimal">463.95137928</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp></logp>
  <hmdb-id></hmdb-id>
  <chembl-id>CHEMBL1878267</chembl-id>
  <chemspider-id>82831</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002803</chemdb-id>
  <dsstox-id>DTXSID7032551</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00008648</susdat-id>
  <iupac>3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine</iupac>
  <moldb-polar-surface-area>116.55999999999999</moldb-polar-surface-area>
  <moldb-refractivity>88.9072</moldb-refractivity>
  <moldb-polarizability>32.1929591655375</moldb-polarizability>
  <moldb-rotatable-bond-count>6</moldb-rotatable-bond-count>
  <moldb-acceptor-count>6</moldb-acceptor-count>
  <moldb-donor-count>1</moldb-donor-count>
  <moldb-pka-strongest-acidic>7.180075754144078</moldb-pka-strongest-acidic>
  <moldb-pka-strongest-basic>2.323087057087631</moldb-pka-strongest-basic>
  <moldb-physiological-charge>0</moldb-physiological-charge>
  <moldb-number-of-rings>2</moldb-number-of-rings>
  <moldb-alogps-logp>3.99</moldb-alogps-logp>
  <moldb-alogps-logs>-6.84</moldb-alogps-logs>
  <moldb-alogps-solubility>6.69e-05 g/l</moldb-alogps-solubility>
  <kingdom>Organic compounds</kingdom>
  <superklass>Benzenoids</superklass>
  <klass>Benzene and substituted derivatives</klass>
  <subklass>Trifluoromethylbenzenes</subklass>
  <paper-count type="integer">574</paper-count>
  <sync-id>CED0010545</sync-id>
  <structure-inchikey>UZCGKGPEKUCDTF-UHFFFAOYSA-N</structure-inchikey>
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  <structure-indexed-at type="dateTime">2026-09-19T04:00:58Z</structure-indexed-at>
</compound>
