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<compound>
  <id type="integer">3953</id>
  <title>T3D3898</title>
  <common-name>Penoxsulam</common-name>
  <description>Penoxsulam is an exogenous organic compound with the formula C16H14F5N5O5S and an average molecular weight of 483.37 g/mol. At room temperature, this substance exists as a solid. Penoxsulam belongs to the benzenesulfonamides, a subclass of benzene and substituted derivatives within the organic compounds.

In industrial applications, penoxsulam is used as an insulator. It has been recorded as being released from floors in building and construction, as well as from electrical and electronic equipment, specifically video games and superconductive or hyperconductive conductors cables or transmission lines. Regarding its biological activity, penoxsulam has six recorded protein targets, which include interstitial collagenase (MMP1), intercellular adhesion molecule 1 (ICAM1), cytochrome P450 3A4 (CYP3A4), and cytochrome P450 2B6 (CYP2B6), along with two other proteins.</description>
  <cas>219714-96-2</cas>
  <pubchem-id>11784975</pubchem-id>
  <chemical-formula>C16H14F5N5O5S</chemical-formula>
  <weight>483.4</weight>
  <appearance>White powder.</appearance>
  <melting-point nil="true"/>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility nil="true"/>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure nil="true"/>
  <target nil="true"/>
  <mechanism-of-toxicity nil="true"/>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>This is a man-made compound that is used as a pesticide.</use-source>
  <min-risk-level nil="true"/>
  <health-effects nil="true"/>
  <symptoms nil="true"/>
  <treatment nil="true"/>
  <created-at type="dateTime">2013-04-25T07:56:53Z</created-at>
  <updated-at type="dateTime">2026-08-19T14:40:17Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia nil="true"/>
  <uniprot-id nil="true"/>
  <kegg-compound-id>C18481</kegg-compound-id>
  <omim-id nil="true"/>
  <chebi-id nil="true"/>
  <biocyc-id nil="true"/>
  <ctd-id nil="true"/>
  <stitch-id nil="true"/>
  <drugbank-id nil="true"/>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>COC1=CN=C(OC)N2N=C(NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)N=C12</moldb-smiles>
  <moldb-formula>C16H14F5N5O5S</moldb-formula>
  <moldb-inchi>InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)</moldb-inchi>
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  <moldb-average-mass type="decimal">483.37</moldb-average-mass>
  <moldb-mono-mass type="decimal">483.063580298</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp>2.9</logp>
  <hmdb-id nil="true"/>
  <chembl-id>CHEMBL1895913</chembl-id>
  <chemspider-id>9959655</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002859</chemdb-id>
  <dsstox-id>DTXSID0034803</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00006425</susdat-id>
  <iupac>2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide</iupac>
  <moldb-polar-surface-area>116.94000000000001</moldb-polar-surface-area>
  <moldb-refractivity>109.1229</moldb-refractivity>
  <moldb-polarizability>39.5957870006659</moldb-polarizability>
  <moldb-rotatable-bond-count>8</moldb-rotatable-bond-count>
  <moldb-acceptor-count>8</moldb-acceptor-count>
  <moldb-donor-count>1</moldb-donor-count>
  <moldb-pka-strongest-acidic>6.5484351172797055</moldb-pka-strongest-acidic>
  <moldb-pka-strongest-basic>-1.0787462799649017</moldb-pka-strongest-basic>
  <moldb-physiological-charge>-1</moldb-physiological-charge>
  <moldb-number-of-rings>3</moldb-number-of-rings>
  <moldb-alogps-logp>3.13</moldb-alogps-logp>
  <moldb-alogps-logs>-3.63</moldb-alogps-logs>
  <moldb-alogps-solubility>1.13e-01 g/l</moldb-alogps-solubility>
  <kingdom>Organic compounds</kingdom>
  <superklass>Benzenoids</superklass>
  <klass>Benzene and substituted derivatives</klass>
  <subklass>Benzenesulfonamides</subklass>
  <paper-count type="integer">134</paper-count>
  <sync-id>CED0013771</sync-id>
  <structure-inchikey>SYJGKVOENHZYMQ-UHFFFAOYSA-N</structure-inchikey>
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  <structure-indexed-at type="dateTime">2026-09-19T04:00:59Z</structure-indexed-at>
</compound>
