<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">3959</id>
  <title>T3D3904</title>
  <common-name>Prohexadione-calcium</common-name>
  <description>Prohexadione-calcium is a plant growth regulator that inhibits gibberellin metabolism. It is frequently used as a growth-retardant compound for apples. Prohexidione-calcium is known to reduce terminal growth by inhibiting 2-oxoglutarate-dependent dioxygenases, which are involved in the formation of growth-specific gibberellins (e.g., the conversion of GA20 to GA1), a group of plant hormones that are primarily responsible for regulation of shoot elongation in apple trees. In addition, it is also known that prohexadione-calcium interferes with ethylene biosynthesis and flavonoid metabolism, which can influence other responses in the plant.</description>
  <cas>127277-53-6</cas>
  <pubchem-id>9868965</pubchem-id>
  <chemical-formula>C20H22CaO10</chemical-formula>
  <weight nil="true"/>
  <appearance>White powder.</appearance>
  <melting-point nil="true"/>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility nil="true"/>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure nil="true"/>
  <target nil="true"/>
  <mechanism-of-toxicity nil="true"/>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source nil="true"/>
  <min-risk-level nil="true"/>
  <health-effects nil="true"/>
  <symptoms nil="true"/>
  <treatment nil="true"/>
  <created-at type="dateTime">2013-04-25T07:56:53Z</created-at>
  <updated-at type="dateTime">2026-04-03T08:51:27Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia nil="true"/>
  <uniprot-id nil="true"/>
  <kegg-compound-id nil="true"/>
  <omim-id nil="true"/>
  <chebi-id nil="true"/>
  <biocyc-id nil="true"/>
  <ctd-id nil="true"/>
  <stitch-id nil="true"/>
  <drugbank-id nil="true"/>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>[Ca++].CCC(=O)C1C(=O)CC(CC1=O)C([O-])=O.CCC(=O)C1C(=O)CC(CC1=O)C([O-])=O</moldb-smiles>
  <moldb-formula>C20H22CaO10</moldb-formula>
  <moldb-inchi>InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,9H,2-4H2,1H3,(H,14,15);/q;;+2/p-2</moldb-inchi>
  <moldb-inchikey>SAZAPFZGSHYFGB-UHFFFAOYSA-L</moldb-inchikey>
  <moldb-average-mass type="decimal">462.461</moldb-average-mass>
  <moldb-mono-mass type="decimal">462.083888079</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp nil="true"/>
  <hmdb-id nil="true"/>
  <chembl-id nil="true"/>
  <chemspider-id>8044656</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002865</chemdb-id>
  <dsstox-id>DTXSID9034496</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00020973</susdat-id>
  <iupac>calcium bis(3,5-dioxo-4-propanoylcyclohexane-1-carboxylate)</iupac>
</compound>
