<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">4358</id>
  <title>T3D4304</title>
  <common-name>Hydroxypropionic acid</common-name>
  <description>3-Hydroxypropionic acid is a carboxylic acid. It is used in the production of various chemicals such as acrylates in industry. It can be produced by certain microbes. Its chemical structure is similar to L-serine.</description>
  <cas>503-66-2</cas>
  <pubchem-id>68152</pubchem-id>
  <chemical-formula>C3H6O3</chemical-formula>
  <weight nil="true"/>
  <appearance nil="true"/>
  <melting-point>&lt; 25°C</melting-point>
  <boiling-point>143°C (sodium salt) decomposes</boiling-point>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure nil="true"/>
  <target nil="true"/>
  <mechanism-of-toxicity>3-hydroxypropionic acid (3HP) toxicity is mediated by 3-hydroxypropionic aldehyde (reuterin). 3HP toxicity is also proposed to be related to inhibition of the chorismate and threonine super-pathways. Generally, the toxicity mechanism of 3HP is not understood at the molecular level. (A15450)</mechanism-of-toxicity>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.</use-source>
  <min-risk-level nil="true"/>
  <health-effects>Chronically high levels of hydroxypropionic acid are associated with at least 5 inborn errors of metabolism including: Biotinidase deficiency, Malonic Aciduria, Methylmalonate Semialdehyde Dehydrogenase Deficiency, Methylmalonic Aciduria, Methylmalonic, Aciduria Due to Cobalamin-Related Disorders and Propionic acidemia.</health-effects>
  <symptoms nil="true"/>
  <treatment nil="true"/>
  <created-at type="dateTime">2014-08-29T06:17:33Z</created-at>
  <updated-at type="dateTime">2026-04-04T02:21:28Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>Hydroxypropionic acid</wikipedia>
  <uniprot-id nil="true"/>
  <kegg-compound-id>C01013</kegg-compound-id>
  <omim-id nil="true"/>
  <chebi-id>33404</chebi-id>
  <biocyc-id nil="true"/>
  <ctd-id nil="true"/>
  <stitch-id nil="true"/>
  <drugbank-id>DB03688</drugbank-id>
  <pdb-id>3OH</pdb-id>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>OCCC(O)=O</moldb-smiles>
  <moldb-formula>C3H6O3</moldb-formula>
  <moldb-inchi>InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)</moldb-inchi>
  <moldb-inchikey>ALRHLSYJTWAHJZ-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">90.0779</moldb-average-mass>
  <moldb-mono-mass type="decimal">90.031694058</moldb-mono-mass>
  <origin>Endogenous</origin>
  <state>Liquid</state>
  <logp nil="true"/>
  <hmdb-id>HMDB00700</hmdb-id>
  <chembl-id>CHEMBL1205969</chembl-id>
  <chemspider-id>61460</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM003264</chemdb-id>
  <dsstox-id>DTXSID50198305</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id nil="true"/>
  <iupac>3-hydroxypropanoic acid</iupac>
</compound>
