4481 3-O-Sulfogalactosylceramide (d18:1/24:0) 3-O-Sulfogalactosylceramide (d18:1/24:0) belongs to the glycosphingolipids, a subclass of sphingolipids within the organic compounds. With an average molecular weight of 892.32 g/mol, 3-O-Sulfogalactosylceramide (d18:1/24:0) is a heavy molecule. This endogenous compound has the chemical formula C48H93NO11S and exists as a solid at room temperature. It is detected in the kidney, brain, and myelin tissues. Often known as sulfatide, this acidic, sulfated glycosphingolipid is found in various cell type membranes, particularly in myelin, where it constitutes 3-4% of total membrane lipids. It is synthesized primarily in the central nervous system's oligodendrocytes from galactocerebrosides and activated sulfate, 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Accumulation of this lipid in the lysosomes is a characteristic of metachromatic leukodystrophy, a lysosomal storage disease caused by arylsulfatase A deficiency. Additionally, alterations in its homeostasis, trafficking, and metabolism are present in the earliest clinically recognizable stages of Alzheimer's disease. 151122-71-3 6451121 C48H93NO11S White powder. No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-08-29T06:51:14Z 2026-04-14T15:20:32Z Sulfatide C06125 60361 GALACTOSYLCERAMIDE-SULFATE DB04780 true CCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](OS(O)(=O)=O)[C@H]1O)[C@H](O)\C=C\CCCCCCCCCCCCC C48H93NO11S InChI=1S/C48H93NO11S/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2)40-58-48-46(54)47(60-61(55,56)57)45(53)43(39-50)59-48/h35,37,41-43,45-48,50-51,53-54H,3-34,36,38-40H2,1-2H3,(H,49,52)(H,55,56,57)/b37-35+/t41-,42+,43+,45-,46+,47-,48+/m0/s1 MEAZTWJVOWHKJM-CIAPRIGGSA-N 892.317 891.646933513 Endogenous Solid HMDB00024 4953605 CHEM003387 192.07999999999998 244.98880000000005 111.22108904014226 43 10 6 -1.8538312164292199 0.025242039687316864 -1 1 6.01 -6.63 2.09e-04 g/l Organic compounds Lipids and lipid-like molecules Sphingolipids Glycosphingolipids 8 CED0037463 MEAZTWJVOWHKJM-CIAPRIGGSA-N 40000000004000000000800000000600000000000020000000020002100000000000000002000000000000020000000000004000000000100000000000000000000000000000000000018000200000000020800000000300000000000000000001000021010001000000000000000021000000100000000000000000000000100000400040000000000000000002010080000000000000000000200000401000000002000810000000080000000001000000000088000000080100000008000000200008020000000000008000000200000000000000020000000000080080000002000000000000000000000000010440000002000000400100000000000000 5010800085128600c1c0135081b8a280080014b885152060013c20548330a84c6442005013b000400700412800c0002004600b24809c32250344657980a24000c71104011a801420429012d002f202000804858851211eb350040462440009110c38012f0848022045181201d5f4006460e680500101e504b118024002591002504008184ef0820a08070250492c0008391c181245409e0a7308082060c00480404310130090c0300a040d60076d35124ac000418941084010004a30c8408212a02102a41499113201c00686555142980c010010032450428d6012200801030490304d1008810b2013480401d912208e0070043080c2842e1001998058080006 776t3gAAAAAQAAAAAwAAAAAAAAA9AAAAPQAAAIABBgBgAAAAAQMGAGAAAAAC AgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGAGAA AAACAgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIG AGAAAAACAgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAA AgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAKAAAAAMECAAo AAAAAwIHAGgAAAADAgEGIDQAAAABAQQGAGAAAAACAggAIAAAAAIGIDQAAAAC AQQIACAAAAACBiA0AAAAAgEEBgBgAAAAAgIIAGAAAAABAQYgNAAAAAIBBAgA YAAAAAEBBiA0AAAAAgEECAAgAAAAAhAAIAAAAAYIAGAAAAABAQgAKAAAAAMC CAAoAAAAAwIGIDQAAAABAQQIAGAAAAABAQYgNAAAAAIBBAgAYAAAAAEBBgBo AAAAAwMBBgBoAAAAAwMBBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAA AgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBg AAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAQMLAAEAAQIAAgMAAwQABAUA BQYABgcABwgACAkACQoACgsACwwADA0ADQ4ADg8ADxAAEBEAERIAEhMAExQA FBUAFRYAFhcAFxgoAhcZIBkaABobABscABwdAB0eAB4fAB8gACAhAB8iACIj ACIkACQlACUmACYnACYoCAImKQgCJCoAKisAGiwALC0ALC4EAy4vCgIDAiww LzAEAzAxADEyADIzADM0ADQ1ADU2ADY3ADc4ADg5ADk6ADo7ADs8ACodAEIB AAAABh0qJCIfHhcEAAAAAAAAABY= 2026-09-19T04:01:16Z