4526 Maleylacetoacetic acid Maleylacetoacetic acid is an endogenous solid with the formula C8H8O6 and an average molecular weight of 200.15 g/mol. Maleylacetoacetic acid belongs to the medium-chain keto acids and derivatives, a subclass of keto acids and derivatives within the organic compounds. It is an intermediate in the metabolism of tyrosine. The enzyme homogentisate 1,2-dioxygenase, or HGD, catalyzes the conversion of homogentisate to 4-maleylacetoacetate. This enzyme is involved in the catabolism of aromatic rings, specifically in the breakdown of phenylalanine and tyrosine. One recorded source for this compound is Building & Construction (Tents Or Canopies). 5698-52-2 5280393 C8H8O6 200.14 White powder. No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-08-29T06:51:36Z 2026-08-25T04:24:32Z Maleylacetoacetate C01036 47904 4-MALEYL-ACETOACETATE true OC(=O)CC(=O)CC(=O)\C=C/C(O)=O C8H8O6 InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1- GACSIVHAIFQKTC-UPHRSURJSA-N 200.1455 200.032087988 Endogenous Solid -0.7 HMDB02052 CHEMBL1743220 4444078 CHEM003432 NS00121524 (Z)-4,6-dioxooct-2-enedioic acid 108.74000000000001 44.397400000000005 16.75405859034148 6 6 2 2.716169602537572 -7.0576341820437145 -2 0 -0.19 -2.08 1.65e+00 g/l Organic compounds Organic acids and derivatives Keto acids and derivatives Medium-chain keto acids and derivatives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 ï¾­Þ�������������������� ���€���h��������(�������(�������`�������(�������(�������`�������(�������(�������h��������h��������(�������h��������(�������� ��(�������������������(�� $� *����� �$��� � (�B�������������� 2026-09-19T04:01:18Z