4806 T3D4751 Dihydrotestosterone Dihydrotestosterone is a potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid. -- Pubchem; Dihydrotestosterone (DHT) (INN: androstanolone) is a biologically active metabolite of the hormone testosterone, formed primarily in the prostate gland, testes, hair follicles, and adrenal glands by the enzyme 5-alpha-reductase by means of reducing the alpha 4,5 double-bond. Dihydrotestosterone belongs to the class of compounds called androgens, also commonly called androgenic hormones or testoids. DHT is thought to be approximately 30 times more potent than testosterone because of increased affinity to the androgen receptor. -- Wikipedia. 521-18-6 10635 C19H30O2 White powder. 181°C 525 mg/mL at 25°C Bioavailability is very low (0-2%) following oral administration. No indication of carcinogenicity to humans (not listed by IARC). Dihydrotestosterone is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-09-11T05:14:48Z 2026-05-14T17:47:05Z http://en.wikipedia.org/wiki/Dihydrotestosterone C03917 16330 17-BETA-HYDROXY-5ALPHA-ANDROSTAN-3-O DB02901 DHT true [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C C19H30O2 InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1 NVKAWKQGWWIWPM-ABEVXSGRSA-N 290.4403 290.224580204 Endogenous Solid 3.55 HMDB02961 14 <p>A. Glenn Braswell, Aftab J. Ahmed, &#8220;Composition for inhibiting production of dihydrotestosterone to treat benign prostate hyperplasia.&#8221; U.S. Patent US6264996, issued October, 1996.</p> CHEM003708 DTXSID9022364 (1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-one 37.3 83.60309999999998 34.537342899421 0 2 1 19.37770535655329 -0.8839915294840951 0 4 3.37 -4.46 9.98e-03 g/l