4862 Oxybenzone Oxybenzone belongs to the benzophenones, a subclass of benzene and substituted derivatives within the organic compounds. This exogenous solid has the formula C14H12O3 and an average molecular weight of 228.24 g/mol. Industrially, it is utilized as a UV stabilizer, fragrance, and stabilizer (PMC13188146). Biologically, it acts as a xenoestrogen (PMC10880820). It serves as a protein target inhibitor for the Estrogen receptor (ESR1), Aromatase (CYP19A1), Androgen receptor (AR), and Estrogen receptor beta (ESR2), among two other proteins. Oxybenzone is used in various plastics, including Polyurethane, Polycarbonate, Polystyrene, Polyamide, Polyvinyl Chloride, Acrylonitrile butadiene styrene, Polypropylene, Low-Density Polyethylene, and High-Density Polyethylene, and is released in Polyethylene Terephthalate. It is found in or released from 28 recorded sources, including Household items such as Credit Card Holders; Building & Construction materials like Tents Or Canopies and Sunshades Awnings Or Outside Screens; Food, food processing & cookware including Food Preservation, Processing Fish, and Food contact materials; Household cleaning & consumer products such as Soap Detergents, Bleaching Agents, Cigar Cigarettes, Non Electric Simulated Smoking Devices, and Perfumes Within Detergents And Soaps; and Electrical & Electronic Equipment including Antennas, Communication Cables Or Conductors, Conductors Or Conductive Bodies Characterised By The Conductive Materials, Discharge Lamps, and Electric Hearing Aids. Recorded exposure routes include oral, touch, and inhalation, the latter of which is supported by literature (PMC10005944). Health effects associated with oxybenzone include depression (PMC12578804) and an increase in arthritis (PMC11382499). Additionally, the compound has been detected in the urine of individuals with Prostate cancer (PMC11311772). 131-57-7 4632 C14H12O3 228.24 White powder. 65.5°C 155°C at 5.00E+00 mm Hg Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin. Route of Elimination: In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine. No indication of carcinogenicity to humans (not listed by IARC). Used as an ingredient in sunscreen and other cosmetics. 2014-09-11T05:17:27Z 2026-05-14T17:00:21Z Oxybenzone C14285 34283 C005290 DB01428 true COC1=CC(O)=C(C=C1)C(=O)C1=CC=CC=C1 C14H12O3 InChI=1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3 DXGLGDHPHMLXJC-UHFFFAOYSA-N 228.2433 228.07864425 Exogenous Solid 3.79 HMDB15497 CHEMBL1625 4471 CHEM003764 DTXSID3022405 2-benzoyl-5-methoxyphenol 46.53 65.07760000000002 23.96111181175272 3 3 1 7.073430637559264 -4.848677912480104 0 2 3.35 -3.25 1.28e-01 g/l Organic compounds Benzenoids Benzene and substituted derivatives Benzophenones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 ï¾­Þ������������������������€���`�������(������@(������@h�������@(�������h�������@(������@h�������@h��������(�������(������@(������@h�������@h�������@h�������@h�������@h������������ ��h���h��� ��h���h���h�� (� � ��h�� h� �h���h���h���h���h�B������������� �������������� 2026-09-19T04:01:31Z