<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">4979</id>
  <title>T3D4924</title>
  <common-name>Flavone</common-name>
  <description>Quercetin is a flavonoid that forms the "backbone" for many other flavonoids, including the citrus flavonoids rutin, hesperidin, naringin and tangeritin. In studies, quercetin is found to be the most active of the flavonoids, and many medicinal plants owe much of their activity to their high quercetin content. Quercetin has demonstrated significant anti-inflammatory activity because of direct inhibition of several initial processes of inflammation. For example, it inhibits both the manufacture and release of histamine and other allergic/inflammatory mediators. In addition, it exerts potent antioxidant activity and vitamin C-sparing action.</description>
  <cas>525-82-6</cas>
  <pubchem-id>10680</pubchem-id>
  <chemical-formula>C15H10O2</chemical-formula>
  <weight nil="true"/>
  <appearance>White powder.</appearance>
  <melting-point>100°C</melting-point>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility nil="true"/>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure nil="true"/>
  <target nil="true"/>
  <mechanism-of-toxicity nil="true"/>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>In studies, quercetin is found to be the most active of the flavonoids, and many medicinal plants owe much of their activity to their high quercetin content.</use-source>
  <min-risk-level nil="true"/>
  <health-effects nil="true"/>
  <symptoms nil="true"/>
  <treatment nil="true"/>
  <created-at type="dateTime">2014-09-11T05:22:42Z</created-at>
  <updated-at type="dateTime">2026-03-27T01:52:51Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>http://en.wikipedia.org/wiki/Flavone</wikipedia>
  <uniprot-id nil="true"/>
  <kegg-compound-id>C10043</kegg-compound-id>
  <omim-id nil="true"/>
  <chebi-id>42491</chebi-id>
  <biocyc-id>CPD-6641</biocyc-id>
  <ctd-id>C043562</ctd-id>
  <stitch-id nil="true"/>
  <drugbank-id>DB07776</drugbank-id>
  <pdb-id>FLN</pdb-id>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>O=C1C=C(OC2=CC=CC=C12)C1=CC=CC=C1</moldb-smiles>
  <moldb-formula>C15H10O2</moldb-formula>
  <moldb-inchi>InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H</moldb-inchi>
  <moldb-inchikey>VHBFFQKBGNRLFZ-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">222.2387</moldb-average-mass>
  <moldb-mono-mass type="decimal">222.068079564</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp>3.56</logp>
  <hmdb-id>HMDB03075</hmdb-id>
  <chembl-id nil="true"/>
  <chemspider-id>10230</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM003880</chemdb-id>
  <dsstox-id>DTXSID2022048</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00007856</susdat-id>
  <iupac>2-phenyl-4H-chromen-4-one</iupac>
</compound>
