17881 <common-name>Methazolamide</common-name> <description nil="true"/> <cas>554-57-4</cas> <pubchem-id>4100</pubchem-id> <chemical-formula>C5H8N4O3S2</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2016-05-22T03:43:23Z</created-at> <updated-at type="dateTime">2026-05-14T16:46:34Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB00703</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CN1N=C(SC1=NC(C)=O)S(N)(=O)=O</moldb-smiles> <moldb-formula>C5H8N4O3S2</moldb-formula> <moldb-inchi>InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)</moldb-inchi> <moldb-inchikey>FLOSMHQXBMRNHR-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">236.26</moldb-average-mass> <moldb-mono-mass type="decimal">236.003782482</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>-0.59</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id>3958</chemspider-id> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM016776</chemdb-id> <dsstox-id>DTXSID1023281</dsstox-id> <toxcast-id>23281</toxcast-id> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00007349</susdat-id> <iupac>N-[(2E)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide</iupac> <moldb-polar-surface-area>105.19</moldb-polar-surface-area> <moldb-refractivity>51.29710000000001</moldb-refractivity> <moldb-polarizability>20.988367995724253</moldb-polarizability> <moldb-rotatable-bond-count>1</moldb-rotatable-bond-count> <moldb-acceptor-count>6</moldb-acceptor-count> <moldb-donor-count>1</moldb-donor-count> <moldb-pka-strongest-acidic>7.208445537006113</moldb-pka-strongest-acidic> <moldb-pka-strongest-basic>-3.640455179599608</moldb-pka-strongest-basic> <moldb-physiological-charge>0</moldb-physiological-charge> <moldb-number-of-rings>1</moldb-number-of-rings> <moldb-alogps-logp>-0.20</moldb-alogps-logp> <moldb-alogps-logs>-2.13</moldb-alogps-logs> <moldb-alogps-solubility>1.74e+00 g/l</moldb-alogps-solubility> </compound>