Identification Common Name 7alpha,27-Dihydroxycholesterol Class Small Molecule Description 7-a,27-dihydroxycholesterol is an intermediate in bile acid biosynthesis. The enzyme 27-Hydroxycholesterol 7alpha-monooxygenase [EC:1.14.13.60] catalyzes the production of this metabolite from 27-hydroxycholesterol. This enzyme reaction is irreversible and occurs in the endoplasmic reticulum. Contaminant Sources Contaminant Type Not Available Chemical Structure Synonyms Value Source 5-Cholestene-3beta,7alpha,26-triol ChEBI 7-alpha,27-Dihydroxycholesterol ChEBI Cholest-5-ene-3beta,7alpha,26-triol ChEBI Cholest-5-ene-3beta,7alpha,27-triol ChEBI 5-Cholestene-3b,7a,26-triol Generator 5-Cholestene-3β,7α,26-triol Generator 7-Α,27-dihydroxycholesterol Generator Cholest-5-ene-3b,7a,26-triol Generator Cholest-5-ene-3β,7α,26-triol Generator Cholest-5-ene-3b,7a,27-triol Generator Cholest-5-ene-3β,7α,27-triol Generator Cholest-5-ene-3,7,27-triol MeSH 7alpha,26-Dihydroxycholesterol HMDB 7alpha,27-Dihydroxycholesterol HMDB Cholest-5-ene-3- b,7-a,27-triol HMDB Cholest-5-ene-3-b,7-a,27-triol HMDB Cholest-5-ene-3-beta,7-alpha,27-triol HMDB
Chemical Formula C27 H46 O3 Average Molecular Mass 418.652 g/mol Monoisotopic Mass 418.345 g/mol CAS Registry Number 4725-24-0 IUPAC Name (1S,2R,5S,9S,10S,11S,14R,15R)-14-[(2R)-7-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-ene-5,9-diol Traditional Name 7α,27-dihydroxycholesterol SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)CO InChI Identifier InChI=1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17?,18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1 InChI Key RXMHNAKZMGJANZ-DTTSCKGMSA-N Chemical Taxonomy Description belongs to the class of organic compounds known as trihydroxy bile acids, alcohols and derivatives. These are prenol lipids structurally characterized by a bile acid or alcohol which bears three hydroxyl groups. Kingdom Organic compounds Super Class Lipids and lipid-like molecules Class Steroids and steroid derivatives Sub Class Bile acids, alcohols and derivatives Direct Parent Trihydroxy bile acids, alcohols and derivatives Alternative Parents Substituents 26-hydroxysteroid
Trihydroxy bile acid, alcohol, or derivatives
3-hydroxy-delta-5-steroid
3-hydroxysteroid
7-hydroxysteroid
3-beta-hydroxysteroid
3-beta-hydroxy-delta-5-steroid
Hydroxysteroid
Delta-5-steroid
Fatty alcohol
Fatty acyl
Cyclic alcohol
Secondary alcohol
Primary alcohol
Organic oxygen compound
Alcohol
Hydrocarbon derivative
Organooxygen compound
Aliphatic homopolycyclic compound Molecular Framework Aliphatic homopolycyclic compounds External Descriptors 
