126323 <common-name>(-)-Thalidomide arene oxide</common-name> <description>(-)-Thalidomide arene oxide is an organic compound with the formula C13H10N2O5 and an average molecular weight of 274.23 g/mol. (-)-Thalidomide arene oxide belongs to the isoindolines, a subclass of isoindoles and derivatives within the organic compounds. This substance has been identified in or released from 13 recorded sources across multiple sectors. Within the healthcare, pharmaceuticals & veterinary products sector, it is associated with medical devices. In the energy, oil & gas and industrial manufacturing & chemical processing sectors, it is found in lubricants. Its presence is also recorded in food packaging within the food, food processing & cookware sector, as well as in synthetic textiles and carpets and rugs within the textiles, leather & furnishings sector. Additionally, it is linked to electrical & electronic equipment, including batteries, printed circuit boards, capacitors, wires and cables, and cell phones, along with one other sector. Recorded routes of exposure for this compound include oral, inhalation, and touch.</description> <cas nil="true"/> <pubchem-id>154699796</pubchem-id> <chemical-formula>C13H10N2O5</chemical-formula> <weight>274.23</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-06T09:54:41Z</created-at> <updated-at type="dateTime">2026-08-27T22:51:31Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C1CC(=O)NC(=O)[C@H]1N2C(=O)C3=CC4C(O4)C=C3C2=O</moldb-smiles> <moldb-formula>C13H10N2O5</moldb-formula> <moldb-inchi>InChI=1S/C13H10N2O5/c16-10-2-1-7(11(17)14-10)15-12(18)5-3-8-9(20-8)4-6(5)13(15)19/h3-4,7-9H,1-2H2,(H,14,16,17)/t7-,8?,9?/m0/s1</moldb-inchi> <moldb-inchikey>MLUCRLHVMELD-UEJVZZJDSA-N</moldb-inchikey> <moldb-average-mass type="decimal" nil="true"/> <moldb-mono-mass type="decimal">274.0589714</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>-1.4</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM122216</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00117529</susdat-id> <iupac>4-[(3S)-2,6-dioxopiperidin-3-yl]-1a,6a-dihydrooxireno[2,3-f]isoindole-3,5-dione</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Isoindoles and derivatives</klass> <subklass>Isoindolines</subklass> <paper-count type="integer">144</paper-count> <sync-id>CED0016989</sync-id> <structure-inchikey>MNALUCRLHVMELD-UEJVZZJDSA-N</structure-inchikey> <structure-fingerprint>40000000000001000000020000000000000000000000000000000000020000000000000000000000000000000000000000000000000000004000000000000000000000000000020840000000000000000000000000000000000000000000000000000010000000002020100000000000000000000100020000008000000000000200000000000010000000100000000000001000000002000008004000000000000080000000000400000000000000000002000000000000000010000000000000000000000000000000000000000200000000000000000000000000000000040000000000060000000002000000004400000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAAUAAAAFwAAAIABBgBgAAAAAgIGAGAAAAAC AgYAKAAAAAMECAAoAAAAAwIHAGgAAAADAgEGACgAAAADBAgAKAAAAAMCBiA0 AAAAAQEEBwAoAAAAAwMGACgAAAADBAgAKAAAAAMCBgAoAAAAAwQGAGgAAAAD AwEGAGAAAAADAQYAYAAAAAMBCAAgAAAAAgYAaAAAAAMDAQYAKAAAAAMEBgAo AAAAAwQIACgAAAADAgsAAQABAgACAygCAgQgBAUgBQYoAgUHAAcIAAgJIAkK KAIJCyALDCgCDA0ADQ4ADg8ADhAAEBEoAhESIBITKAIHAAASCCARCyAPDQBC BAAAAAYABwUEAgEFCQgSEQsGDA0OEBELAw8ODRcEAAAAAAAAABY= </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:47:50Z</structure-indexed-at> </compound>