<common-name>APG-1387</common-name> <description>APG-1387 is an organic compound with the chemical formula C60H72N10O10S2. APG-1387 belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 1,157 g/mol, APG-1387 is a heavy molecule. In terms of biological activity, there are six recorded protein targets for this compound. APG-1387 acts as an inhibitor of E3 ubiquitin-protein ligase XIAP, as well as Baculoviral IAP repeat-containing protein 1 (NAIP), Baculoviral IAP repeat-containing protein 2 (BIRC2), and Baculoviral IAP repeat-containing protein 3 (BIRC3). Additionally, it targets two other proteins.</description> <cas>1570231-89-8</cas> <pubchem-id>73336238</pubchem-id> <chemical-formula>C60H72N10O10S2</chemical-formula> <weight>1157.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T20:35:51Z</created-at> <updated-at type="dateTime">2026-08-23T03:10:14Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id 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<synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM133559</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(5S,8S,10aR)-3-(3-{[(5S,8S,10aR)-8-[(diphenylmethyl)carbamoyl]-5-[(2S)-2-(methylamino)propanamido]-6-oxo-decahydropyrrolo[1,2-a][1,5]diazocin-3-yl]sulfonyl}benzenesulfonyl)-N-(diphenylmethyl)-5-[(2S)-2-(methylamino)propanamido]-6-oxo-decahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organic acids and derivatives</superklass> <klass>Carboxylic acids and derivatives</klass> <subklass>Amino acids, peptides, and analogues</subklass> <paper-count type="integer">122</paper-count> <sync-id>CED0017889</sync-id> <structure-inchikey>AKLBERUGKZNEJY-RTEPGWBGSA-N</structure-inchikey> <structure-fingerprint>440020000000000000000000001004000001000000000000000000000000000000000010000000210000200200000000940000000000000000000000000000000000100000000005004000000000000000210000000040008000000010000400000000008100000000010000001000000000040201000000000000040000001000010000400000008000000000000002c0000000008100000000000040000000000000000024000000000400080200000000020000000200088000000000000000000000000400000000000000000000000000000000000040000600000000000000000000000000000040000001120480400000000000000000800000000004</structure-fingerprint> 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<=(�<>�>?�>@�@A��B�BC(�BD DE�EF�FGh�GHh�HIh�IJh�JKh�EL�LMh�MNh�NOh�OPh�PQh��h�#��4/h�:5h�KFh�QLh��B �� "#��01234/�6789:5�GHIJKF�MNOPQL��</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:50:31Z</structure-indexed-at> </compound>

137666 <common-name>APG-1387</common-name> <description>APG-1387 is an organic compound with the chemical formula C60H72N10O10S2. APG-1387 belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 1,157 g/mol, APG-1387 is a heavy molecule. In terms of biological activity, there are six recorded protein targets for this compound. APG-1387 acts as an inhibitor of E3 ubiquitin-protein ligase XIAP, as well as Baculoviral IAP repeat-containing protein 1 (NAIP), Baculoviral IAP repeat-containing protein 2 (BIRC2), and Baculoviral IAP repeat-containing protein 3 (BIRC3). Additionally, it targets two other proteins.</description> <cas>1570231-89-8</cas> <pubchem-id>73336238</pubchem-id> <chemical-formula>C60H72N10O10S2</chemical-formula> <weight>1157.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T20:35:51Z</created-at> <updated-at type="dateTime">2026-08-23T03:10:14Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB16095</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>[H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)S(=O)(=O)C1=CC(=CC=C1)S(=O)(=O)N1CC[C@@]2([H])CC[C@H](N2C(=O)[C@H](C1)NC(=O)[C@H](C)NC)C(=O)NC(C1=CC=CC=C1)C1=CC=CC=C1)NC(=O)[C@H](C)NC)C(=O)NC(C1=CC=CC=C1)C1=CC=CC=C1</moldb-smiles> <moldb-formula>C60H72N10O10S2</moldb-formula> 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<synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM133559</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(5S,8S,10aR)-3-(3-{[(5S,8S,10aR)-8-[(diphenylmethyl)carbamoyl]-5-[(2S)-2-(methylamino)propanamido]-6-oxo-decahydropyrrolo[1,2-a][1,5]diazocin-3-yl]sulfonyl}benzenesulfonyl)-N-(diphenylmethyl)-5-[(2S)-2-(methylamino)propanamido]-6-oxo-decahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organic acids and derivatives</superklass> <klass>Carboxylic acids and derivatives</klass> <subklass>Amino acids, peptides, and analogues</subklass> <paper-count type="integer">122</paper-count> <sync-id>CED0017889</sync-id> <structure-inchikey>AKLBERUGKZNEJY-RTEPGWBGSA-N</structure-inchikey> <structure-fingerprint>440020000000000000000000001004000001000000000000000000000000000000000010000000210000200200000000940000000000000000000000000000000000100000000005004000000000000000210000000040008000000010000400000000008100000000010000001000000000040201000000000000040000001000010000400000008000000000000002c0000000008100000000000040000000000000000024000000000400080200000000020000000200088000000000000000000000000400000000000000000000000000000000000040000600000000000000000000000000000040000001120480400000000000000000800000000004</structure-fingerprint> 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<=(�<>�>?�>@�@A��B�BC(�BD DE�EF�FGh�GHh�HIh�IJh�JKh�EL�LMh�MNh�NOh�OPh�PQh��h�#��4/h�:5h�KFh�QLh��B �� "#��01234/�6789:5�GHIJKF�MNOPQL��</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:50:31Z</structure-indexed-at> </compound>