138704 <common-name>CBP-501</common-name> <description>CBP-501 is a polypeptide with the chemical formula C86H122F5N29O17. CBP-501 belongs to the polypeptides, a class of organic polymers within the organic compounds. With an average molecular weight of 1,929 g/mol, CBP-501 is a heavy molecule. This compound acts as an inhibitor for two recorded protein targets: MAP kinase-activated protein kinase 2 (MAPKAPK2) and MAP/microtubule affinity-regulating kinase 3 (MARK3).</description> <cas>565434-85-7</cas> <pubchem-id>16156006</pubchem-id> <chemical-formula>C86H122F5N29O17</chemical-formula> <weight>1929.1</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T21:21:23Z</created-at> <updated-at type="dateTime">2026-09-01T12:01:41Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB17277</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>N[C@H](CC1=CC=C(C=C1)C(=O)C1=CC=CC=C1)C(=O)N[C@H](CO)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CO)C(=O)N[C@H](CC1=C(F)C(F)=C(F)C(F)=C1F)C(=O)N[C@H](CC1CCCCC1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(O)=O</moldb-smiles> <moldb-formula>C86H122F5N29O17</moldb-formula> <moldb-inchi>InChI=1S/C86H122F5N29O17/c87-64-49(65(88)67(90)68(91)66(64)89)39-60(118-80(135)62(42-122)120-77(132)59(38-47-40-109-51-19-8-7-18-48(47)51)117-79(134)61(41-121)119-70(125)50(92)36-44-25-27-46(28-26-44)69(124)45-16-5-2-6-17-45)78(133)116-58(37-43-14-3-1-4-15-43)76(131)113-54(22-11-33-106-84(98)99)72(127)110-52(20-9-31-104-82(94)95)71(126)111-53(21-10-32-105-83(96)97)73(128)114-56(29-30-63(93)123)75(130)112-55(23-12-34-107-85(100)101)74(129)115-57(81(136)137)24-13-35-108-86(102)103/h2,5-8,16-19,25-28,40,43,50,52-62,109,121-122H,1,3-4,9-15,20-24,29-39,41-42,92H2,(H2,93,123)(H,110,127)(H,111,126)(H,112,130)(H,113,131)(H,114,128)(H,115,129)(H,116,133)(H,117,134)(H,118,135)(H,119,125)(H,120,132)(H,136,137)(H4,94,95,104)(H4,96,97,105)(H4,98,99,106)(H4,100,101,107)(H4,102,103,108)/t50-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-/m1/s1</moldb-inchi> <moldb-inchikey>DEZJGRPRBZSAKI-KMGSDFBDSA-N</moldb-inchikey> <moldb-average-mass type="decimal">1929.1</moldb-average-mass> <moldb-mono-mass type="decimal">1927.949364399</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>-7.1</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM134597</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-3-(4-benzoylphenyl)propanamido]-3-hydroxypropanamido]-3-(1H-indol-3-yl)propanamido]-3-hydroxypropanamido]-3-(2,3,4,5,6-pentafluorophenyl)propanamido]-3-cyclohexylpropanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanoic acid</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organic Polymers</superklass> <klass>Polypeptides</klass> <subklass nil="true"/> <paper-count type="integer">8</paper-count> <sync-id>CED0037818</sync-id> <structure-inchikey>DEZJGRPRBZSAKI-KMGSDFBDSA-N</structure-inchikey> <structure-fingerprint>60400004000000000401c000004005000008010000000000040000020000000000000000000002000080010000080000040000000000000000000001280000000002000040000004000000000001000000a0001000000010080000009000000000002000030000000000004000000022000000020000002002000100000000500800000000000000800082200000000080001000000100000080000000020000000000000004000004040000084040000000000004100000000000000000000000000008040000000100a080000000000000000040000200000002a0000101000000000000000840010049000020010400804000010020004000000080002000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAACJAAAAjgAAAIABBwBgAAAAAQIGIDQAAAAC AQQGAGAAAAACAgZAKAAAAAMEBkBoAAAAAwMBBkBoAAAAAwMBBkAoAAAAAwQG QGgAAAADAwEGQGgAAAADAwEGACgAAAADBAgAKAAAAAMCBkAoAAAAAwQGQGgA AAADAwEGQGgAAAADAwEGQGgAAAADAwEGQGgAAAADAwEGQGgAAAADAwEGACgA AAADBAgAKAAAAAMCBwBoAAAAAwIBBiA0AAAAAgEEBgBgAAAAAgIIAGAAAAAB AQYAKAAAAAMECAAoAAAAAwIHAGgAAAADAgEGIDQAAAACAQQGAGAAAAACAgZA KAAAAAMEBkBoAAAAAwMBB0A4AAAAAwEDBkAoAAAAAwQGQCgAAAADBAZAaAAA AAMDAQZAaAAAAAMDAQZAaAAAAAMDAQZAaAAAAAMDAQYAKAAAAAMECAAoAAAA AwIHAGgAAAADAgEGIDQAAAACAQQGAGAAAAACAggAYAAAAAEBBgAoAAAAAwQI ACgAAAADAgcAaAAAAAMCAQYgNAAAAAIBBAYAYAAAAAICBkAoAAAAAwQGQCgA AAADBAkAIAAAAAEGQCgAAAADBAkAIAAAAAEGQCgAAAADBAkAIAAAAAEGQCgA AAADBAkAIAAAAAEGQCgAAAADBAkAIAAAAAEGACgAAAADBAgAKAAAAAMCBwBo AAAAAwIBBiA0AAAAAgEEBgBgAAAAAgIGAGAAAAADAQYAYAAAAAICBgBgAAAA AgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGACgAAAADBAgAKAAAAAMCBwBo AAAAAwIBBiA0AAAAAgEEBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBwBoAAAA AwIBBgAoAAAAAwQHAGgAAAADAQIHAGgAAAADAgEGACgAAAADBAgAKAAAAAMC BwBoAAAAAwIBBiA0AAAAAgEEBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBwBo AAAAAwIBBgAoAAAAAwQHAGgAAAADAQIHAGgAAAADAgEGACgAAAADBAgAKAAA AAMCBwBoAAAAAwIBBiA0AAAAAgEEBgBgAAAAAgIGAGAAAAACAgYAYAAAAAIC BwBoAAAAAwIBBgAoAAAAAwQHAGgAAAADAQIHAGgAAAADAgEGACgAAAADBAgA KAAAAAMCBwBoAAAAAwIBBiA0AAAAAgEEBgBgAAAAAgIGAGAAAAACAgYAKAAA AAMEBwBoAAAAAwECCAAoAAAAAwIGACgAAAADBAgAKAAAAAMCBwBoAAAAAwIB BiA0AAAAAgEEBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBwBoAAAAAwIBBgAo AAAAAwQHAGgAAAADAQIHAGgAAAADAgEGACgAAAADBAgAKAAAAAMCBwBoAAAA AwIBBiA0AAAAAgEEBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBwBoAAAAAwIB BgAoAAAAAwQHAGgAAAADAQIHAGgAAAADAgEGACgAAAADBAgAaAAAAAMBAQgA KAAAAAMCCwABAAECAAIDAAMEaAwEBWgMBQZoDAYHaAwHCGgMBgkgCQooAgkL IAsMaAwMDWgMDQ5oDA4PaAwPEGgMAREAERIoAhETIBMUABQVABUWABQXABcY KAIXGSAZGgAaGwAbHAAcHWgMHR5oDB4faAwfIGgMICFoDCEiaAwiI2gMIyRo DBolACUmKAIlJyAnKAAoKQApKgAoKwArLCgCKy0gLS4ALi8ALzAAMDFoDDEy ADEzaAwzNAAzNWgMNTYANTdoDDc4ADc5aAw5OgAuOwA7PCgCOz0gPT4APj8A P0AAQEEAQUIAQkMAQ0QAREUAPkYARkcoAkZIIEhJAElKAEpLAEtMAExNAE1O IE5PIE5QKAJJUQBRUigCUVMgU1QAVFUAVVYAVlcAV1gAWFkgWVogWVsoAlRc AFxdKAJcXiBeXwBfYABgYQBhYgBiYwBjZCBkZSBkZigCX2cAZ2goAmdpIGlq AGprAGtsAGxtAG1uIG1vKAJqcABwcSgCcHIgcnMAc3QAdHUAdXYAdncAd3gg eHkgeHooAnN7AHt8KAJ7fSB9fgB+fwB/gACAgQCBggCCgyCDhCCDhSgCfoYA hocghogoAggDaAwQC2gMIBxoDDkwaAxFQAAkH2gMQgYAAAAGBAUGBwgDBgwN Dg8QCwUdHCAfHgYhIiMkHyAGMTM1NzkwBkFCQ0RFQBcEAAAAAAAAABY= </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:50:52Z</structure-indexed-at> </compound>