140721 <common-name>Elisidepsin</common-name> <description>Elisidepsin is a chemical compound with the molecular formula C75H124N14O16. With an average molecular weight of 1,478 g/mol, Elisidepsin is a heavy molecule. In terms of biological activity, it is recorded as an inhibitor of the protein target Receptor tyrosine-protein kinase erbB-3 (ERBB3).</description> <cas>681272-30-0</cas> <pubchem-id nil="true"/> <chemical-formula>C75H124N14O16</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T16:50:59Z</created-at> <updated-at type="dateTime">2026-05-14T20:15:32Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB19522</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>[H][C@](NC(=O)[C@H](NC(=O)CC[C@@H](C)CC)C(C)C)([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N1CCC[C@]1([H])C(=O)N[C@@H](CCCN)C(=O)N[C@]([H])([C@@H](C)CC)C(=O)N[C@@H]1[C@@H](C)OC(=O)[C@@H](NC(=O)\C(NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](NC(=O)[C@]([H])(NC1=O)[C@@H](C)CC)C(C)C)=C\C)C(C)C</moldb-smiles> <moldb-formula>C75H124N14O16</moldb-formula> <moldb-inchi>InChI=1S/C75H124N14O16/c1-20-43(15)33-34-53(91)80-54(38(5)6)68(97)87-61(46(18)90)72(101)82-56(40(9)10)69(98)83-57(41(11)12)74(103)89-36-28-32-52(89)66(95)78-50(31-27-35-76)64(93)85-59(44(16)21-2)71(100)88-62-47(19)105-75(104)58(42(13)14)84-63(92)49(23-4)77-65(94)51(37-48-29-25-24-26-30-48)79-67(96)55(39(7)8)81-70(99)60(45(17)22-3)86-73(62)102/h23-26,29-30,38-47,50-52,54-62,90H,20-22,27-28,31-37,76H2,1-19H3,(H,77,94)(H,78,95)(H,79,96)(H,80,91)(H,81,99)(H,82,101)(H,83,98)(H,84,92)(H,85,93)(H,86,102)(H,87,97)(H,88,100)/b49-23-/t43-,44-,45-,46+,47-,50-,51-,52-,54+,55+,56-,57+,58-,59-,60-,61+,62+/m0/s1</moldb-inchi> <moldb-inchikey>ZNVCPJPCKSJWDH-IPZJCCDYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">1477.899</moldb-average-mass> <moldb-mono-mass type="decimal">1476.931973969</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM136614</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac nil="true"/> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom nil="true"/> <superklass nil="true"/> <klass nil="true"/> <subklass nil="true"/> <paper-count type="integer">104</paper-count> <sync-id>CED0018795</sync-id> <structure-inchikey>ZNVCPJPCKSJWDH-UCTDCHLSSA-N</structure-inchikey> <structure-fingerprint>40000000006000000080c000000c1400200100000000000040000000104020040000001002042020000000002000000214000000000000020020000000800010000010100000000c0000010000008000002080000000420000102000902200000000001001000000040800000080000100000002010400040080040000000110082000004824000080000222000000008000120000010000020000800000000000000014000400000000400408005008000000000000880000800000200c002201800008000040000040200000000040000000440002010000000220000400400000000500008000400040000000010400000000020000000000200000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAABpAAAAawAAAIABBiA0AAAAAQEEBwBoAAAA AwIBBgAoAAAAAwQIACgAAAADAgYgNAAAAAIBBAcAaAAAAAMCAQYAKAAAAAME CAAoAAAAAwIGAGAAAAACAgYAYAAAAAICBiA0AAAAAQEEBgBgAAAAAQMGAGAA AAACAgYAYAAAAAEDBgBgAAAAAwEGAGAAAAABAwYAYAAAAAEDBiA0AAAAAQEE BgBgAAAAAQMIAGAAAAABAQYAKAAAAAMECAAoAAAAAwIHAGgAAAADAgEGIDQA AAABAQQGAGAAAAADAQYAYAAAAAEDBgBgAAAAAQMGACgAAAADBAgAKAAAAAMC BwBoAAAAAwIBBiA0AAAAAgEEBgBgAAAAAwEGAGAAAAABAwYAYAAAAAEDBgAo AAAAAwQIACgAAAADAgcAKAAAAAMDBgBgAAAAAgIGAGAAAAACAgYAYAAAAAIC BiA0AAAAAgEEBgAoAAAAAwQIACgAAAADAgcAaAAAAAMCAQYgNAAAAAEBBAYA YAAAAAICBgBgAAAAAgIGAGAAAAACAgcAYAAAAAECBgAoAAAAAwQIACgAAAAD AgcAaAAAAAMCAQYgNAAAAAIBBAYgNAAAAAEBBAYAYAAAAAEDBgBgAAAAAgIG AGAAAAABAwYAKAAAAAMECAAoAAAAAwIHAGgAAAADAgEGIDQAAAACAQQGIDQA AAABAQQGAGAAAAABAwgAKAAAAAMCBgAoAAAAAwQIACgAAAADAgYgNAAAAAEB BAcAaAAAAAMCAQYAKAAAAAMECAAoAAAAAwIGACgAAAADBAcAaAAAAAMCAQYA KAAAAAMECAAoAAAAAwIGIDQAAAACAQQGAGAAAAACAgZAKAAAAAMEBkBoAAAA AwMBBkBoAAAAAwMBBkBoAAAAAwMBBkBoAAAAAwMBBkBoAAAAAwMBBwBoAAAA AwIBBgAoAAAAAwQIACgAAAADAgYgNAAAAAIBBAcAaAAAAAMCAQYAKAAAAAME CAAoAAAAAwIGIDQAAAACAQQHAGgAAAADAgEGACgAAAADBAgAKAAAAAMCBiA0 AAAAAQEEBgBgAAAAAQMGAGAAAAACAgYAYAAAAAEDBgBgAAAAAwEGAGAAAAAB AwYAYAAAAAEDBgBoAAAAAwMBBgBgAAAAAQMGAGAAAAADAQYAYAAAAAEDBgBg AAAAAQMLAAEAAQIgAgMoAgIEAAQFAAUGIAYHKAIGCAAICQAJCgAKCwAKDAAM DQAEDgAODwAOEAAAEQAREgAREwAAFAAUFSgCFBYgFhcAFxgAGBkAGBoAFxsA GxwoAhsdIB0eAB4fAB8gAB8hAB4iACIjKAIiJCAkJQAlJgAmJwAnKAAoKQAp KigCKSsgKywALC0ALS4ALi8ALzAALDEAMTIoAjEzIDM0ADQ1ADU2ADU3ADc4 ADQ5ADk6KAI5OyA7PAA8PQA9PgA9PwA/QCBAQSgCQEIAQkMAQ0QgREUoAkRG JANGRyBHSCBISSgCSEoASksAS0wATE1oDE1OaAxOT2gMT1BoDFBRaAxKUgBS UyBTVCgCU1UAVVYAVlcgV1goAldZAFlaAFpbIFtcKAJZXQBdXgBdXwBfYABV YQBhYgBhYwBGZCoCAgJHZWRlBANCZgBmZwBmaAAoJABbPABRTGgMQgMAAAAF JCUmJygTPTxbWllXVlVTUkpIR0ZEQ0JAPwZNTk9QUUwXBAAAAAAAAAAW </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:51:28Z</structure-indexed-at> </compound>