140841 <common-name>Bexlosteride</common-name> <description>Bexlosteride is an organic compound with the formula C14H16ClNO and an average molecular weight of 249.74 g/mol. Bexlosteride belongs to the benzoquinolines, a subclass of quinolines and derivatives within the organic compounds. It is classified as an organoheterocyclic compound. Regarding its biological activity, it acts as an inhibitor of the protein target 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1).</description> <cas>148905-78-6</cas> <pubchem-id>166562</pubchem-id> <chemical-formula>C14H16ClNO</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T17:00:12Z</created-at> <updated-at type="dateTime">2026-05-14T20:18:53Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB19798</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>[H][C@@]12CCC3=CC(Cl)=CC=C3[C@@]1([H])CCC(=O)N2C</moldb-smiles> <moldb-formula>C14H16ClNO</moldb-formula> <moldb-inchi>InChI=1S/C14H16ClNO/c1-16-13-6-2-9-8-10(15)3-4-11(9)12(13)5-7-14(16)17/h3-4,8,12-13H,2,5-7H2,1H3/t12-,13+/m1/s1</moldb-inchi> <moldb-inchikey>WQBIOEFDDDEARX-CHWSQXEVSA-N</moldb-inchikey> <moldb-average-mass type="decimal">249.74</moldb-average-mass> <moldb-mono-mass type="decimal">249.0920418</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM136734</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac nil="true"/> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Quinolines and derivatives</klass> <subklass>Benzoquinolines</subklass> <paper-count type="integer">3</paper-count> <sync-id>CED0046725</sync-id> <structure-inchikey>WQBIOEFDDDEARX-CHWSQXEVSA-N</structure-inchikey> <structure-fingerprint>400000000000880000000040000000000000020000000000000000040000000000000000100000000000000000000000000400000000000000000000020000000000000004000000000000000000002000080000000000000120000000000020100000000000000008000101001000060004000000020000000004000000000000000000000080000000000000000000004000000000000080000000200000000000000000001000000000000000000000000000000000000000008000010400000000000200200000000000000000000000000000040000000000000000000000000000000000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAARAAAAEwAAAIABBiA0AAAAAgEEBgBgAAAA AgIGAGAAAAACAgZAKAAAAAMEBkBoAAAAAwMBBkAoAAAAAwQRACAAAAABBkBo AAAAAwMBBkBoAAAAAwMBBkAoAAAAAwQGIDQAAAABAQQGAGAAAAACAgYAYAAA AAICBgAoAAAAAwQIACgAAAADAgcAKAAAAAMDBgBgAAAAAQMLAAEAAQIAAgMA AwRoDAQFaAwFBgAFB2gMBwhoDAgJaAwJCgAKCwALDAAMDQANDigCDQ8gDxAA CgAADwAACQNoDEIDAAAABgECAwkKAAYEBQcICQMGCwwNDwAKFwQAAAAAAAAA Fg== </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:51:33Z</structure-indexed-at> </compound>