141872 <common-name>Icotrokinra</common-name> <description>Icotrokinra is a compound with the chemical formula C90H120N20O22S2. With an average molecular weight of 1,898 g/mol, Icotrokinra is a heavy molecule. In terms of its biological activity, it functions as an antagonist of the Interleukin-23 receptor (IL23R).</description> <cas>2763602-16-8</cas> <pubchem-id nil="true"/> <chemical-formula>C90H120N20O22S2</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T18:19:58Z</created-at> <updated-at type="dateTime">2026-05-14T20:50:10Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB21724</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C[C@@H](O)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(C)=O)C(C)(C)SSC(C)(C)[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3C)NC1=O)C(=O)N[C@@H](CC1=CC=C(OCCN)C=C1)C(=O)N[C@@H](CC1=CC2=CC=CC=C2C=C1)C(=O)NC1(CCOCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CN=C1)C(=O)N(C)CC(N)=O</moldb-smiles> <moldb-formula>C90H120N20O22S2</moldb-formula> 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<structure-indexed-at type="dateTime">2026-09-19T04:52:33Z</structure-indexed-at> </compound>